<p>This disclosure relates to hybrid proteins including at least two polypeptide chains, with each polypeptide chain including an amino acid sequence of a cytokine or a fragment thereof linked to an amino acid sequence of a subunit of a heterodimeric proteinaceous hormone. Also disclosed are methods of making and using such hybrid proteins in the treatment of various diseases.</p>
申请公布号
WO2007047829(A2)
申请公布日期
2007.04.26
申请号
WO2006US40860
申请日期
2006.10.17
申请人
APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.;MCKENNA, SEAN, D.;CAMPBELL, ROBERT, K.;JIANG, XULIANG;DE LUCA, GIAMPIERO;YANG, MEIJIA