PROCESS FOR THE PREPARATION OF STRONTIUM RANELATE

摘要

A process for the preparation of strontium ranelate or a hydrate thereof is provided comprising (a) reacting a tetraester compound of Formula II: wherein R, R₁, R₂, and R₃ are independently a linear or branched C₁-C₆alkyl group or a substituted or unsubstituted C₃-C₁₂ cyclic group, in the presence of a lithium base and in a solvent with an inorganic acid salt of strontium.