| 摘要 |
PROBLEM TO BE SOLVED: To provide a method for producing a purine nucleoside by a fermentation method. SOLUTION: Bacteria, belonging to the genus Escherichia, modified so that the reaction branched from a purine nucleoside biosynthesis to other metabolic products, and being a reaction catalyzed by an enzyme selected from a succinyl-adenosine monophosphate synthase and purine nucleoside phosphorylase can be blocked, and having purine nucleoside-producing abilities, are cultured in a medium to allow the purine nucleoside to be formed and accumulated, and the purine nucleoside is collected. COPYRIGHT: (C)2007,JPO&INPIT
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