EXPRESSION OF RBAP48 IN MEMORY AND AGING AND METHODS RELATED THERETO

摘要

This invention provides a method for increasing the expression of RbAp48 protein in a eukaryotic cell comprising introducing into the cell an agent which specifically increases the expression of RbAp48 protein in the cell. This invention also provides a method for treating a subject afflicted with age- related memory decline comprising administering to the subject a therapeutically effective amount of an agent which specifically increases the expression of RbAp48 protein in the cells of .the subject's brain. This invention further provides a method for determining whether an agent causes an increase in the expression of RbAp48 protein. Finally, this invention provides a method for determining whether an agent causes an increase in the activity of RbAp48 protein.