发明名称 |
ErbB4 antagonists |
摘要 |
The present invention concerns methods and means for controlling excessive proliferation and/or migration of smooth muscle cells, and in particular for treating stenosis, by using antagonists of a native ErbB4 receptor. The invention further concerns a method for the identification of ErbB4 agonists and antagonists capable of inhibiting or enhancing the proliferation or migration of smooth muscle cells.
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申请公布号 |
US2007092513(A1) |
申请公布日期 |
2007.04.26 |
申请号 |
US20060581221 |
申请日期 |
2006.10.13 |
申请人 |
GERRITSEN MARY E;SLIWKOWSKI MARK X |
发明人 |
GERRITSEN MARY E.;SLIWKOWSKI MARK X. |
分类号 |
A61K39/395;G01N33/50;A61K38/00;A61K45/00;A61K48/00;A61P9/00;A61P9/12;A61P13/10;A61P21/00;C07K14/475;C07K14/82;C07K16/32;C07K16/40;C12N15/02;C12P21/08;G01N33/15;G01N33/53;G01N33/566 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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