| 摘要 |
Compounds are provided which have the structure of formula (1), wherein A, B, C, D, m, Y, Ra, Rc, Rd, and Rd' are as described herein, and which are useful as inhibitors of tryptase, thrombin, trypsin, Factor Xa, Factor Vila, Factor XIa, and urokinase-type plasminogen activator and may be employed in preventing and/or treating asthma, chronic asthma, allergic rhinitis, and thrombotic disorders. |
| 申请人 |
DAIAMED, INC.;BANNISTER, THOMAS;CELATKA, CASSANDRA;CHANDRAKUMAR, NIZAL, S;DENG, HONGFENG;GUO, ZIHONG;JIN, LEI;LAZAROVA, TSVETELINA;LIN, JIAN;MOE, SCOTT, T.;NAGAFUJI, PAMELA;NAVIA, MANUEL;RIPKA, AMY;RYNKIEWICZ, MICHAEL, J;SPEAR, KERRY, L;STRICKLER, JAMES, E;XIE, ROGER |
发明人 |
BANNISTER, THOMAS;CELATKA, CASSANDRA;CHANDRAKUMAR, NIZAL, S;DENG, HONGFENG;GUO, ZIHONG;JIN, LEI;LAZAROVA, TSVETELINA;LIN, JIAN;MOE, SCOTT, T.;NAGAFUJI, PAMELA;NAVIA, MANUEL;RIPKA, AMY;RYNKIEWICZ, MICHAEL, J;SPEAR, KERRY, L;STRICKLER, JAMES, E;XIE, ROGER |
