发明名称 |
CELL LINES HARBORING HEPATITIS VIRUS AND METHODS FOR USING THEREOF |
摘要 |
<p>The present invention relates to cryopreserved primary hepatocytes infected with hepatitis C virus (HCV), which, when thawed and cultured, are capable of being infected with and releasing infectious HCV. The present invention also relates to methods of producing primary cryopreserved hepatocytes infected with hepatitis C virus (HCV), wherein the HCV-infected primary hepatocytes are capable of releasing new infectious HCV. The present invention also relates to methods of using HCV-infected primary hepatocytes to screen drug candidates for their ability to affect HCV infection and/or replication. The invention also relates to methods of producing infectious HCV in vitro and methods of using this infectious HCV such as, but not limited to, preparing vaccines directed towards HCV, its receptor or virus-receptor intermediate states.</p> |
申请公布号 |
WO2007046962(A2) |
申请公布日期 |
2007.04.26 |
申请号 |
WO2006US34442 |
申请日期 |
2006.09.05 |
申请人 |
THE UNIVERSITY OF MARYLAND, BALTIMORE;OLDACH, DAVID;HEYWARD, SCOTT;SILBER, PAUL |
发明人 |
OLDACH, DAVID;HEYWARD, SCOTT;SILBER, PAUL |
分类号 |
C12N7/00 |
主分类号 |
C12N7/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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