| 摘要 |
<p>An anti-IL-6 receptor antibody is examined with respect to its amelioration effect on the state of an obstruction area in cardiac infarction and its inhibitory effect on left ventricular remodeling after cardiac infarction occurs. As a result, it is found that, when the anti-IL-6 receptor antibody is administered, the increase in MPO activity in an obstruction area in cardiac infarction can be significantly prevented and the expression of myocardial MCP-1 can also be prevented in both an obstruction area and a non-obstruction area. Based on the findings of an ultrasonographic examination and a histological examination of the heart, it is also found that hypercardia can be prevented.</p> |
