| 发明名称 |
TRISUBSTITUTED AMINES AS PHOSPHODIESTERASE 4 INHIBITORS |
| 摘要 |
PDE4 inhibition is achieved by novel compounds,' e.g., N-substituted diarylamine analogs. The compounds of the present invention are of Formulas I-III; (I), (II) and (III) wherein A, B, D, E, G, J, K, R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>11</SUP>, R<SUP>12</SUP>, R<SUP>13</SUP>, R<SUP>14</SUP>, R<SUP>21</SUP>, R<SUP>22</SUP>, R<SUP>23</SUP> and R<SUP>24</SUP> are as defined herein. |
| 申请公布号 |
WO2006135828(A3) |
申请公布日期 |
2007.04.26 |
| 申请号 |
WO2006US22655 |
申请日期 |
2006.06.09 |
| 申请人 |
MEMORY PHARMACEUTICALS CORPORATION;F. HOFFMANN-LA ROCHE AG;TALAMAS, FRANCISCO, XAVIER;CAROON, JOAN, MARIE;DUNN, ROBERT;HOPPER, ALLEN;KUESTER, ERIC;SCHUMACHER, RICHARD;TEHIM, ASHOK |
发明人 |
TALAMAS, FRANCISCO, XAVIER;CAROON, JOAN, MARIE;DUNN, ROBERT;HOPPER, ALLEN;KUESTER, ERIC;SCHUMACHER, RICHARD;TEHIM, ASHOK |
| 分类号 |
C07D211/58;A61K31/4427;A61K31/4468;A61P29/00;C07D401/12;C07D403/12;C07D409/14;C07D413/12;C07D417/12;C07D417/14 |
主分类号 |
C07D211/58 |
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