A NEW HUMAN T-CELL LYMPHOTROPIC VIRUS (HTLV-3): NUCLEIC ACID AND PEPTIDIC SEQUENCES THEREOF AND METHOD FOR DETECTING HTLV-3

摘要

The genetic sequence of HTL V-3, a human T-lymphotropic virus distinct from HTLV-1 and HTLV-2, is provided. In addition, the sequences of the polypeptides encoded by the genome of HTLV-3 are provided. These polypeptides allow the production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, and the use of such nucleic acids and polypeptides in diagnostic methods, kits, immunogenic composition, or antiviral therapy. Diagnostic assays also include amplification-based and hybridization-based assays that rely on primers or probes from the genetic sequence of the HTLV-3 genome.