Stable liquid pharmaceutical formulations of botulinium toxin and its use

摘要

A stable liquid pharmaceutical formulation, comprising a serum albumin, a pharmaceutically acceptable buffer capable of providing a buffered pH range between pH 5 and pH 6 and isolated botulinium toxin, wherein said formulation is stable as a liquid for at least one year at a temperature between 0 and 10 °C, or at least 6 months at a temperature between 10 and 30 °C, and its use in the manufacture of medicaments for various therapeutic and cosmetic treatments.