| 发明名称 |
1,4-disubstituted isoquinilone derivatives as raf-kinase inhibitors useful for the treatment of proliferative diseases |
| 摘要 |
This invention relates to compounds of the formula (I) wherein the variable substituents are described herein. The compounds are useful for the treatment of conditions and diseases characterized by an aberrant MAP kinase signaling pathway, such as cancer. |
| 申请公布号 |
ZA200602004(B) |
申请公布日期 |
2007.04.25 |
| 申请号 |
ZA20060002004 |
申请日期 |
2006.03.09 |
| 申请人 |
NOVARTIS AG. |
发明人 |
FINK, CYNTHIA ANNE;PEREZ, LAWRENCE B.;RAMSEY, TIMOTHY MICHAEL;YUSUFF, NAEEM;VERSACE, RICHARD WILLIAM;BATT, DAVID BRYANT;SABIO, MICHAEL LLOYD;KIM, SUNKYU |
| 分类号 |
A61K31/4725;A61P35/00;C07D;C07D217/22;C07D401/04;C07D401/14;C07D405/04;C07D405/14;C07D409/14;C07D413/04;C07D413/10;C07D413/14;C07D417/14 |
主分类号 |
A61K31/4725 |
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