| 摘要 |
Compounds of the general formula II wherein the group R is selected from alkylcarbonyl; or alkoxycarbonyl; wherein any alkyl group is optionally substituted with aryl, amino, alkoxycarbonylamino, mono-alkyl-amino, di-alkyl amino, N-alkyl, N-alkoxycarbonyl-amino, or a carboxylic acid residue (-COOH), or any combination thereof; provided that: R is not unsubstituted acetyl unless simultaneously the stereochemistry of C3 is a and of C25 is S; R is not unsubstituted ethoxycarbonyl when simultaneously the stereochemistry of C3 is S(?) and of C25 is R; R is not succinyl when simultaneously the stereochemistry of C3 is S(?) and of C25 is S or the stereochemistry of C3 is R (?) or S (?) and of C25 is R ; and R is not propionyl, butyryl, valeryl, isovaleryl, capryl, isocaproyl,diethylacetyl, octanoyl, decanol, lauryl, myristyl, palmityl, stearyl, benzoyl, phenylacetyl, phenylpropionate, cinnamate, p-nitrobenzoate, 3,5-dinitrobenzoate, p-chlorobenzoate, 2,4-dichlorobenzoyl, p-bromobenzoyl, m-bromobenzoyl, p-methoxybenzoyl, furoyl, phthalyl when the stereochemistry of C25 is R and the stereochemistry of C3 is S (?); including, subject to the provisos set out above, all stereoisomers and racemic mixtures thereof, and salts thereof. |
