| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a compound which can be useful as a cannabinoid receptor ligand. Ž<P>SOLUTION: A compound of formula (I), or a pharmaceutically acceptable salt of the compound exhibits anti-inflammatory and immunomodulatory activity. A pharmaceutical composition contains the compound. The compound can be useful in the treatment of various medical conditions including cutaneous T-cell lymphoma, rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, glaucoma, diabetes, sepsis, shock, sarcoidosis, idiopathic pulmonary fibrosis, bronchopulmonary dysplasia, retinal disease, scleroderma, osteoporosis, renal ischemia, myocardial infarction, cerebral stroke, cerebral ischemia, nephritis, hepatitis, glomerulonephritis, cryptogenic fibrosing aveolitis, psoriasis, transplant rejection, atopic dermatitis, vasculitis, allergy, seasonal allergic rhinitis, Crohn's disease, inflammatory bowel disease, reversible airway obstruction, adult respiratory distress syndrome, asthma, chronic obstructive pulmonary disease (COPD) or bronchitis. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
|
