发明名称 VARIANT FC REGIONS
摘要 The present invention provides polypeptides, particularly therapeutic antibodies, comprising a novel, variant Fc region. Furthermore the invention provides variant Fc regions which confer an altered effector function or altered serum half life upon a polypeptide to which it is operable attached.
申请公布号 EP1776384(A2) 申请公布日期 2007.04.25
申请号 EP20050773014 申请日期 2005.07.18
申请人 APPLIED MOLECULAR EVOLUTION INC. 发明人 ALLAN, BARRETT;JIANG, WEIDONG;TANG, YING;WATKINS, JEFFRY DEAN
分类号 C07K16/00;A61K39/395;C12N5/10;C12N15/12 主分类号 C07K16/00
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