Piperazine derivatives and their use as therapeutic agents

摘要

Compounds for treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the compounds are of formula (I):
where G, J, L, M, x, y, W, V, R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 8a , R 9 , R 9a , R 10 , R 10a , R 11 and R 11a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.