Gamma secretase inhibitors

摘要

This invention discloses novel gamma secretase inhibitors of the formula: wherein: R¹ is a substituted aryl or substituted heteroaryl group; R² is an R¹ group, alkyl, -X(CO)Y, or alkylene-X(CO)Y wherein X and Y are as defined herein; each R³ and each R^3A are independently H, or alkyl; R¹¹ is aryl, heteroaryl, alkyl, cycloalkyl, arylalkyl, arylcycloalkyl, heteroarylalkyl, heteroarylcycloalkyl, arylheterocycloalkyl, or alkoxyalkyl. Also disclosed is a method of treating Alzheimer's Disease using one or more compounds of the invention.