发明名称 |
VIRTUAL COLONOSCOPY WITH RADIOLABELED PHOSPHOLIPID ETHER ANALOGS |
摘要 |
<p>The present invention provides agents and methods for dual modality virtual colonoscopy that gives both anatomical and functional information using hybrid CT/PET scanning. In preferred embodiments, the present invention provides radiolabeled tumor-specific agents and methods for distinguishing benign polyps from malignant tumors. In further embodiments, the present invention provides compositions and methods useful for distinguishing morphological and functional subregions of a selected region of tissue based on relative levels of phospholipid metabolism. Preferred radiolabeled tumor-specific agents are phospholipid ether analogs labeled with a halogen radioisotope. In certain preferred embodiments, the compositions including radiolabeled phospholipid ether analogs have therapeutic actions in addition to functionally identifying malignant tissue.</p> |
申请公布号 |
EP1773408(A2) |
申请公布日期 |
2007.04.18 |
申请号 |
EP20050769481 |
申请日期 |
2005.07.08 |
申请人 |
CELLECTAR, LLC |
发明人 |
WEICHERT, JAMEY, P.;LONGINO, MARC, A. |
分类号 |
A61K51/04 |
主分类号 |
A61K51/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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