主权项 |
1. A method for determining the likelihood of breast cancer progression, comprising:
a) determining the expression levels of hsa-miR-210 and at least one gene selected from a group consisting of: RB1, BRCA1, FANCD, FANCF, PP2CA, PARP1, NLK, CDH1, EHMT1 and EGFRkin-, in a sample containing breast cancer cells from a subject with breast cancer, and b) comparing the expression levels from step a) to a standard miRNA and gene expression levels in a control sample, wherein higher expression of hsa-miR-210 in the subject with breast cancer, and decreased levels of at least one gene selected from a group consisting of: RB1, BRCA1, FANCD, FANCF, PP2CA, PARP1, NLK, CDH1, EHMT1 and EGFRkin-, as compared to the expression levels in the control sample, correlates with a higher risk of progression. |