| 发明名称 |
ENGINEERED RECOMBINANT ENZYMES FOR METHANE OXIDATION |
| 摘要 |
Provided herein are soluble engineered polypeptides for oxidizing hydrocarbons, and methods of use, manufacture, and design thereof. In particular, soluble, polypeptides capable of oxidizing methane to methanol (e.g., hydroxylation) are provided. |
| 申请公布号 |
US2016265003(A1) |
申请公布日期 |
2016.09.15 |
| 申请号 |
US201615065266 |
申请日期 |
2016.03.09 |
| 申请人 |
Northwestern University ;California Institute of Technology ;Protabit LLC |
发明人 |
Rosenzweig Amy C;Lawton Thomas J.;Nisthal Alex;Kostecki Jan S.;Privett Heidi K.;Lee Fredrick;Olafson Barry;Dousis Athanasios D. |
| 分类号 |
C12P7/04;C10L1/02;C12M1/40;C12M1/00;C12N9/02;C12N11/00 |
主分类号 |
C12P7/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A soluble polypeptide comprising a core sequence having at least 60% but less than 100% sequence identity with SEQ ID NO: 23, wherein the soluble polypeptide is capable of converting an alkane into an alkanol, and wherein the core sequence is C-terminally- and/or N-terminally-flanked by one or more soluble peptide segments. |
| 地址 |
Evanston IL US |
