| 发明名称 |
Inhibitors of p38 |
| 摘要 |
The present invention relates to inhibitors of p38, a mammalian protein kinase involved cell proliferation, cell death and response to extracellular stimuli. The invention also relates to methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing those compositions in the treatment and prevention of various disorders.
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| 申请公布号 |
US7205305(B2) |
申请公布日期 |
2007.04.17 |
| 申请号 |
US20030622320 |
申请日期 |
2003.07.17 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
BEMIS GUY W;SALITURO FRANCESCO G;DUFFY JOHN P;COCHRAN JOHN E;HARRINGTON EDMUND M;MURCKO MARK A;WILSON KEITH P;SU MICHAEL;GALULLO VINCENT P |
| 分类号 |
C07D213/02;A61K31/44;C07D213/56;C07D213/70;C07D213/75;C07D213/89;C07D237/18;C07D241/12;C07D241/20;C07D401/04;C07D405/04;C07D405/12;C07D409/04;C07D471/04;C07D487/04;C07F9/6561 |
主分类号 |
C07D213/02 |
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