| 发明名称 |
Methods of modulation of the immune system |
| 摘要 |
Manipulation of the EphB6 receptor and its active Eph partners allow for regulation of T cell responses, including TCR signaling, T cell proliferation, and induction of T cell death. Methods of modulating EphB6 are described as well as various therapeutic applications.
|
| 申请公布号 |
US7205113(B2) |
申请公布日期 |
2007.04.17 |
| 申请号 |
US20020169520 |
申请日期 |
2002.10.26 |
| 申请人 |
THE HOSPITAL FOR SICK CHILDREN |
发明人 |
ROIFMAN CHAIM M.;FREYWALD ANDREW;SHARFE NIGEL;GRUNBERGER THOMAS;GRUEBAUM EYAL |
| 分类号 |
G01N33/53;A61K38/00;A61P35/00;A61P37/00;C07K14/52 |
主分类号 |
G01N33/53 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
