发明名称 Multivalent neuraminidase inhibitor conjugates
摘要 The invention relates to a multimeric compound or a pharmaceutically acceptable salt or derivative thereof which comprises three or more neuraminidase-binding groups attached to a spacer or linking group, in which the neuraminidase-binding group is a compound which binds to the active site of influenza virus neuraminidase, but is not cleaved by the neuraminidase. The invention also relates to processes for the preparation of the multimeric compound defined above, pharmaceutical compositions containing them or methods for the treatment and/or prophylaxis of a viral infection involving them.
申请公布号 US7205333(B2) 申请公布日期 2007.04.17
申请号 US20030363988 申请日期 2003.10.14
申请人 WU WEN-YANG;DOWLE MICHAEL DENNIS;JIN BETTY;MACDONALD SIMON JOHN FAWCETT;MASON ANDREW MCMURTRIE;MCCONNELL DARRYL;WATSON KEITH 发明人 WU WEN-YANG;DOWLE MICHAEL DENNIS;JIN BETTY;MACDONALD SIMON JOHN FAWCETT;MASON ANDREW MCMURTRIE;MCCONNELL DARRYL;WATSON KEITH
分类号 A61K31/35;A61K31/351;A61K31/496;A61K45/00;A61P31/12;A61P31/16;A61P43/00;C07D307/02;C07D309/28;C07D405/14;C07D407/14;C07D493/04;C12Q1/04;C12Q1/70;G01N33/569 主分类号 A61K31/35
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