发明名称 Substituted 5-alkynyl pyrimidines having neurotrophic activity
摘要 The present invention relates to a series of novel substituted 5-alkynyl pyrimidines, pharmaceutical compositions which contain them, methods for their preparation, and their use in therapy, particularly in the treatment of neurodegenerative or other neurological disorders of the central and peripheral nervous systems, including age related cognitive disorders such as senility and Alzheimer's disease, nerve injuries, peripheral neuropathies, and seizure disorders such as epilepsy.
申请公布号 US7205297(B2) 申请公布日期 2007.04.17
申请号 US20030333447 申请日期 2003.06.27
申请人 KRENITSKY PHARMACEUTICALS, INC. 发明人 BEAUCHAMP LILIA M.;KRENITSKY THOMAS A.;KELLEY JAMES L.
分类号 C07D239/30;C07D239/34;A61K31/505;A61K31/506;A61K31/5375;A61K31/5377;A61K31/661;A61P3/10;A61P25/00;A61P25/02;A61P25/08;A61P25/18;A61P25/28;C07D239/42;C07D239/46;C07D239/47;C07D239/48;C07D401/04;C07D405/04;C07F9/6512 主分类号 C07D239/30
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