发明名称 |
APPARATUS AND METHOD FOR TRANSDERMAL DELIVERY OF FENTANY-BASED AGENTS. |
摘要 |
<p>An apparatus and method for transdermally delivering a biologically active agent comprising a delivery system having a microprojection member (or system) that includes a plurality of microprojections (or array thereof) that are adapted to pierce through the stratum corneum into the underlying epidermis layer, or epidermis and dermis layers. In one embodiment, the fentanyl-based agent is contained in a biocompatible coating that is applied to the microprojection member. In a further embodiment, the delivery system includes a gel pack having a fentanyl-based agent-containing hydrogel formulation that is disposed on the microprojection member after application to the skin of a patient. In an alternative embodiment, the fentanyl-based agent is contained in both the coating and the hydrogel formulation.</p> |
申请公布号 |
MXPA06011972(A) |
申请公布日期 |
2007.04.16 |
申请号 |
MX2006PA11972 |
申请日期 |
2005.03.18 |
申请人 |
JOHNSON & JOHNSON. |
发明人 |
MAA, YUH-FUN;CORMIER, MICHEL J.N.;DADDONA, PETER;AMERI, MAHMOUD |
分类号 |
A61K9/70;A61K31/445;A61M37/00 |
主分类号 |
A61K9/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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