PROCESS AND APPARATUS FOR MEASURING BINDING EVENTS ON A MICROARRAY OF ELECTRODES
摘要
There is disclosed a process and apparatus for reading electrical current of electrodes on a microarray of electrodes. Those electrodes having binding events are detected by a difference in electrical current flow. Enzymes on targets catalyze the conversion of substrate to product, which is detectable by electrochemical reduction at each electrode on the microarray of electrodes. The apparatus has an integration circuit that provides a voltage output that is measured and recorded over time and used to calculate an average current flow. A potentiometer equalizes voltage at electrodes undergoing measurement compared to grounded electrodes.
申请公布号
WO2007041138(A2)
申请公布日期
2007.04.12
申请号
WO2006US37618
申请日期
2006.09.25
申请人
COMBIMATRIX CORPORATION;PEYVAN, KIA;BIZAK, MICHAEL;CAMPBELL, COLIN;LEE, RAND, WILLIAM
发明人
PEYVAN, KIA;BIZAK, MICHAEL;CAMPBELL, COLIN;LEE, RAND, WILLIAM