发明名称 |
OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PRODUCING SAME |
摘要 |
Disclosed is a method for producing an optically active cyclic alcohol compound represented by the general formula [I] below, wherein a cyclic ketone compound represented by the general formula [II] below is asymmetrically reduced in the presence of (A) an optically active oxazaborolidine compound and a boron hydride compound, or alternatively in the presence of (B) an asymmetric transition metal complex obtained from a transition metal compound and an asymmetric ligand, and a hydrogen donor. Also disclosed is such an optically active cyclic alcohol compound. [I] (In the formula, the symbol is as defined below.) [II] (In the formula, R represents a hydrogen atom or a protective group of an amino group.) |
申请公布号 |
WO2007040240(A1) |
申请公布日期 |
2007.04.12 |
申请号 |
WO2006JP319846 |
申请日期 |
2006.10.04 |
申请人 |
TANABE SEIYAKU CO., LTD.;OKAMOTO, MASAKI;SAKURAGI, AKIRA;MORI, YOSHIKAZU;KISHIDA, MUNEKI |
发明人 |
OKAMOTO, MASAKI;SAKURAGI, AKIRA;MORI, YOSHIKAZU;KISHIDA, MUNEKI |
分类号 |
C07D215/22;A61K31/4709;A61P11/06;A61P43/00;B01J31/02;B01J31/22;C07B53/00;C07B61/00;C07D401/04 |
主分类号 |
C07D215/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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