发明名称 OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PRODUCING SAME
摘要 Disclosed is a method for producing an optically active cyclic alcohol compound represented by the general formula [I] below, wherein a cyclic ketone compound represented by the general formula [II] below is asymmetrically reduced in the presence of (A) an optically active oxazaborolidine compound and a boron hydride compound, or alternatively in the presence of (B) an asymmetric transition metal complex obtained from a transition metal compound and an asymmetric ligand, and a hydrogen donor. Also disclosed is such an optically active cyclic alcohol compound. [I] (In the formula, the symbol is as defined below.) [II] (In the formula, R represents a hydrogen atom or a protective group of an amino group.)
申请公布号 WO2007040240(A1) 申请公布日期 2007.04.12
申请号 WO2006JP319846 申请日期 2006.10.04
申请人 TANABE SEIYAKU CO., LTD.;OKAMOTO, MASAKI;SAKURAGI, AKIRA;MORI, YOSHIKAZU;KISHIDA, MUNEKI 发明人 OKAMOTO, MASAKI;SAKURAGI, AKIRA;MORI, YOSHIKAZU;KISHIDA, MUNEKI
分类号 C07D215/22;A61K31/4709;A61P11/06;A61P43/00;B01J31/02;B01J31/22;C07B53/00;C07B61/00;C07D401/04 主分类号 C07D215/22
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