| 摘要 |
<p>The present invention provides a compound having the formula: wherein, n and m are 1; X1 and X2 are O; R1 is a member selected from unsubstituted phenyl and substituted phenyl; R2 is a member selected from hydrogen, -CN, -OR2A, -L2A-C(O)R2B, -L2B-S(O)2R2C; R3 is a member selected from unsubstituted benzyl and substituted benzyl; R4 is a member selected from hydrogen and substituted or unsubstituted alkyl, wherein if R4 is methyl, then -L1-R1 is not benzyl or -C(O)-O-CH2-CH3; and L1 is a bond; and compositions and methods of using the compounds as glucocorticoid receptor modulators.</p> |
