摘要 |
PROBLEM TO BE SOLVED: To obtain a thiomorpholine compound having excellent tachykinine recipient antagonist activity. SOLUTION: The thiomorpholine compound expressed by general formula [I] (wherein the ring A expresses a benzene ring which may have a substituent; the ring B expresses a benzene ring which may have a substituent; R<SP>1</SP>expresses H, an hydroxyl which may have a substituent, an amino which may have a substituent, an alkyl which may have a substituent, a carbonyl having a substituent, or a halogen atom; R<SP>2</SP>expresses H or an alkyl which may have a substituent; R<SP>3a</SP>and R<SP>3b</SP>are the same or different and express each H, an alkyl which may have a substituent, or a group forming an alkylene group by bonding at terminals; n expresses 1 or 2 integer) or a pharmaceutically permissible salt of the same are claimed. COPYRIGHT: (C)2007,JPO&INPIT
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