发明名称 PYRROLOPYRIMIDINE DERIVATIVES FOR TREATING PROLIFERATIVE DISEASES
摘要 The present invention relates to a compound of formula (I), wherein R<SUB>1</SUB> is a heterocyclic radical or an unsubstituted or substituted aromatic radical; G is C<SUB>1</SUB>-C<SUB>7</SUB>-alkylene, -C(=O)-, or C<SUB>1</SUB>-C<SUB>6</SUB>-alkylene-C(=O)- wherein the carbonyl group is attached to the piperazine moiety; Q is -NH- or -O-, with the proviso that Q is -O- if G is -C(=O)- or C<SUB>1</SUB>-C<SUB>6</SUB>-alkylene-C(=O)-; and X is either not present or C<SUB>1</SUB>-C<SUB>7</SUB>-alkylene, with the proviso that a heterocyclic radical R<SUB>1</SUB> is bonded via a ring carbon atom if X is not present; or a salt thereof, which is useful for treating anti-proliferative diseases.
申请公布号 WO2005075460(A3) 申请公布日期 2007.04.12
申请号 WO2005EP00876 申请日期 2005.01.28
申请人 NOVARTIS AG;NOVARTIS PHARMA GMBH;CARAVATTI, GIORGIO;TRAXLER, PETER;ESSER, THOMAS;HE, HANDAN 发明人 CARAVATTI, GIORGIO;TRAXLER, PETER;ESSER, THOMAS;HE, HANDAN
分类号 C07D487/04;A61K31/495;A61P35/00 主分类号 C07D487/04
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