发明名称 |
PYRROLOPYRIMIDINE DERIVATIVES FOR TREATING PROLIFERATIVE DISEASES |
摘要 |
The present invention relates to a compound of formula (I), wherein R<SUB>1</SUB> is a heterocyclic radical or an unsubstituted or substituted aromatic radical; G is C<SUB>1</SUB>-C<SUB>7</SUB>-alkylene, -C(=O)-, or C<SUB>1</SUB>-C<SUB>6</SUB>-alkylene-C(=O)- wherein the carbonyl group is attached to the piperazine moiety; Q is -NH- or -O-, with the proviso that Q is -O- if G is -C(=O)- or C<SUB>1</SUB>-C<SUB>6</SUB>-alkylene-C(=O)-; and X is either not present or C<SUB>1</SUB>-C<SUB>7</SUB>-alkylene, with the proviso that a heterocyclic radical R<SUB>1</SUB> is bonded via a ring carbon atom if X is not present; or a salt thereof, which is useful for treating anti-proliferative diseases. |
申请公布号 |
WO2005075460(A3) |
申请公布日期 |
2007.04.12 |
申请号 |
WO2005EP00876 |
申请日期 |
2005.01.28 |
申请人 |
NOVARTIS AG;NOVARTIS PHARMA GMBH;CARAVATTI, GIORGIO;TRAXLER, PETER;ESSER, THOMAS;HE, HANDAN |
发明人 |
CARAVATTI, GIORGIO;TRAXLER, PETER;ESSER, THOMAS;HE, HANDAN |
分类号 |
C07D487/04;A61K31/495;A61P35/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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