| 发明名称 |
CCR5 RECEPTOR ANTAGONIST MOLECULES |
| 摘要 |
<p>The invention is directed to komaroviquinone, compound 1, 4 rings, heterocyclic (6,5,6,6-ring system), as CCR5 receptor antagonist, and to a pharmaceutical formulation comprising compound 1. The invention further relates to a use of the pharmaceutical composition comprising CCR5 receptor antagonist compound 1 alone or with one or more antiviral agents or other agents in the treatment of HIV-1.</p> |
| 申请公布号 |
WO2007038875(A1) |
申请公布日期 |
2007.04.12 |
| 申请号 |
WO2006CA01648 |
申请日期 |
2006.10.06 |
| 申请人 |
AVANCE PHARMA INC.;WILLIAMS, ROBERT, D.;FAWZI, AHMAD;LAHLOU, EL HASSANE |
发明人 |
WILLIAMS, ROBERT, D.;FAWZI, AHMAD;LAHLOU, EL HASSANE |
| 分类号 |
C07D311/80;A61K31/05;A61K31/352;A61P31/18;C07C39/17;C07C235/08 |
主分类号 |
C07D311/80 |
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