| 发明名称 |
1H-BENZIMIDAZOLE-4-CARBOXAMIDES SUBSTITUTED WITH PHENYL AT THE 2-POSITION ARE POTENT PARP INHIBITORS |
| 摘要 |
Compounds having formula (I), inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds having formula (I), methods of treatment comprising compounds having formula (I), and methods of inhibiting the PARP enzyme comprising compounds having formula (I). |
| 申请公布号 |
CA2623822(A1) |
申请公布日期 |
2007.04.12 |
| 申请号 |
CA20062623822 |
申请日期 |
2006.09.28 |
| 申请人 |
ABBOTT LABORATORIES |
发明人 |
ZHU, GUI-DONG;THOMAS, SHEELA A.;PENNING, THOMAS D.;GIRANDA, VINCENT L.;GONG, JIANCHUN;GANDHI, VIRAJKUMAR B. |
| 分类号 |
C07D401/10;A61K31/4178;A61K31/454;A61P29/00;A61P31/00;A61P35/00;C07D403/10 |
主分类号 |
C07D401/10 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
