发明名称 |
NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND PHARMACEUTICAL APPLICATION THEREOF |
摘要 |
<p>It is intended to provide a compound represented by the general formula (I): (I) (wherein all the symbols are as defined in the description) which has a p38 MAP kinase inhibitory activity, a salt thereof, an N-oxide thereof, a solvate thereof, or a prodrug thereof. The compound of the invention is useful for preventing or treating a disease in which the abnormal production of a cytokine such as an inflammatory cytokine or a chemokine or overreaction to them is considered to be involved in the cause and aggravation of pathological conditions, in other words, an inflammatory disease, a respiratory disease, a cardiovascular disease, a central nervous system disease or the like, which is a cytokine-mediated disease.</p> |
申请公布号 |
WO2007040208(A1) |
申请公布日期 |
2007.04.12 |
申请号 |
WO2006JP319732 |
申请日期 |
2006.10.02 |
申请人 |
ONO PHARMACEUTICAL CO., LTD.;NAKAI, HISAO;YAMAMOTO, SHINGO;NAKATANI, SHINGO;HIROSAKI, TOMOMI |
发明人 |
NAKAI, HISAO;YAMAMOTO, SHINGO;NAKATANI, SHINGO;HIROSAKI, TOMOMI |
分类号 |
C07D401/04;A61K31/4439;A61K45/00;A61P9/00;A61P11/00;A61P19/02;A61P19/08;A61P29/00;A61P43/00;C07D405/14;C07D413/04;C07D413/14;C07D417/14 |
主分类号 |
C07D401/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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