发明名称 |
Methods for the electrochemical detection of multiple target compounds |
摘要 |
A method of detecting two different target molecules through a single electrode is carried out by (a) providing a conductive oxidation-reduction reaction detection electrode; (b) contacting a sample suspected of containing a first and second target molecule to the electrode under conditions in which the first and second target molecules are deposited on the electrode, wherein the first target molecule comprises a first label and the second target molecule comprises a second label; (c) contacting to the electrode a first transition metal complex that oxidizes the first preselected label in a first oxidation-reduction reaction and a second transition metal complex that oxidizes the first and second labels in a second oxidation-reduction reaction, with the first and second oxidation-reduction reactions producing different detectable signals; (d) detecting the presence of the first target molecule by detecting the first oxidation-reduction reaction; and (e) detecting the presence of the second target molecule by detecting the second oxidation-reduction reaction. Devices for carrying out the method are also described.
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申请公布号 |
US7202028(B2) |
申请公布日期 |
2007.04.10 |
申请号 |
US20020237842 |
申请日期 |
2002.09.09 |
申请人 |
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
THORP H. HOLDEN;YANG IVANA V.;STEWART DAVID H.;GROELKE JOHN W.;SZALAI VERONIKA A. |
分类号 |
C12Q1/68;C12P19/34;C12Q1/00 |
主分类号 |
C12Q1/68 |
代理机构 |
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主权项 |
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地址 |
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