CALCIUM PHOSPHATE ARTIFICIAL BONE AS OSTEOCONDUCTIVE AND BIODEGRADABLE BONE SUBSTITUTE MATERIAL

摘要

The present invention relates to a novel calcium phosphate artificial bone promotive of biocompatible osteoanagenesis, which comprises an ordinary calcium phosphate bone cement a nd a linear polyphosphate. The linear polyphosphate of the calcium phosphate artificial bone comprises 3-200 orthophosphate molecules a nd is used in an amount of 0.001-0.05 % by weight based on the total weight of the calcium phosphate artificial bone. The polyphosphate-containing artificial bone of the present invention is non-toxic to the body and chemically stable, and economically favorable in terms of production cost with superior biodegradability. Thus, the polyphosphate-containing artificial bone of the present invention can replace as osteoconductive and osteoinductive, biodegradable substitute for a conventional bone cements,allografts and autografts which are used in the treatment of defects and fractures in every bone of the body, the cure of osteoporous, th e fillers of implant for dental surgery, the bone substitute for plastic surgery, the substitution of defected bones in the operation on joints, including hip-joint, knee-joint and shoulder joint, and the operation on the vertabra.