发明名称 Bi-functional cancer treatment agents
摘要 A novel fusion protein, comprising a receptor-antagonizing domain and a positive immunomodulator domain, characterized, for example, by its ability to block apoptosis and/or inhibit endocrine response, is useful in treating cancer. For example, a human prolactin antagonist-interleukin 2 (hPRLA-IL-2) fusion protein combines apoptosis induction and immuno-therapy to combat cancer in the breast or prostate.
申请公布号 US7201905(B2) 申请公布日期 2007.04.10
申请号 US20010815306 申请日期 2001.03.23
申请人 GREENVILLE HOSPITAL SYSTEM 发明人 CHEN WEN Y.;WAGNER THOMAS E.
分类号 A61K38/00;A61K39/00;A61P35/00;C07K14/52;C07K14/55;C07K14/57;C07K14/575;C07K19/00;C12N15/16;C12N15/62 主分类号 A61K38/00
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