摘要 |
Disclosed is an aryl-substituted nitrogen-containing heterocyclic compound represented by the formula (I) below or a pharmaceutically acceptable salt thereof. This compound serves as a nociceptin receptor antagonist and is useful as a pharmaceutical agent for treating diseases associated with a nociceptin receptor. (I) [In the formula, A<SUB>1</SUB>, A<SUB>2</SUB> and A<SUB>3</SUB> independently represent a carbon atom or a nitrogen atom, and one or two of A<SUB>1</SUB>, A<SUB>2</SUB> and A<SUB>3</SUB> represent a carbon atom; R<SUP>1</SUP> represents a lower alkyl group or the like; R<SUP>2</SUP> represents a phenyl group which may be substituted by a halogen atom or the like; R<SUP>3</SUP> represents a hydrogen atom, a lower alkyl group or the like; and R<SUP>4</SUP> represents a lower alkyl group or the like.]
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申请人 |
BANYU PHARMACEUTICAL CO., LTD.;OKAMOTO, OSAMU;KOBAYASHI, KENSUKE;ITO, HIROKATSU;TSUJITA, TOMOHIRO;OZAKI, SATOSHI;OHTA, HISASHI |
发明人 |
OKAMOTO, OSAMU;KOBAYASHI, KENSUKE;ITO, HIROKATSU;TSUJITA, TOMOHIRO;OZAKI, SATOSHI;OHTA, HISASHI |