发明名称 PROSTATE STEM CELL ANTIGEN (PSCA) VARIANTS AND SUBSEQUENCES THEREOF
摘要 PSCA and its encoded protein, and variants thereof, are described wherein PSCA exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, PSCA provides a diagnostic, prognostic, propylactic and/or therapeutic target for cancer. The PSCA gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with PSCA can be used in active or passive immunization.
申请公布号 WO2005014780(A3) 申请公布日期 2007.04.05
申请号 WO2004US17231 申请日期 2004.05.28
申请人 AGENSYS, INC.;JAKOBOVITS, AYA;GE, WANGMAO;RAITANO, ARTHUR, B.;CHALLITA-EID, PIA, M. 发明人 JAKOBOVITS, AYA;GE, WANGMAO;RAITANO, ARTHUR, B.;CHALLITA-EID, PIA, M.
分类号 A61K38/00;C07K;C07K14/00;C07K14/47;C07K14/705;C07K16/00;C12N 主分类号 A61K38/00
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