| 摘要 |
A process for preparing amines of the general formula (I) <?in-line-formulae description="In-line Formulae" end="lead"?>R<SUP>1</SUP>R<SUP>2</SUP>CHNR<SUP>3</SUP>R<SUP>4</SUP> (I)<?in-line-formulae description="In-line Formulae" end="tail"?> in which R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3 </SUP>and R<SUP>4 </SUP>are each independently hydrogen, straight-chain or branched, halogenated or halogen-free C<SUB>1</SUB>-C<SUB>12</SUB>-alkyl, C<SUB>3</SUB>-C<SUB>12</SUB>-cycloalkyl, C<SUB>6</SUB>-C<SUB>10</SUB>-aryl or C<SUB>7</SUB>-C<SUB>11</SUB>-aralkyl, by catalytic, hydrogenating amination of carbonyl compounds of the general formula (II) <?in-line-formulae description="In-line Formulae" end="lead"?>R<SUP>1</SUP><SUB>-C(-O)-R</SUB><SUP>2</SUP> (II)<?in-line-formulae description="In-line Formulae" end="tail"?> with nitrogen compounds of the general formula (III) <?in-line-formulae description="In-line Formulae" end="lead"?>HNR<SUP>3</SUP>R<SUP>4</SUP> (III)<?in-line-formulae description="In-line Formulae" end="tail"?> in the presence of bifunctional catalyst systems comprising a.) a hydrogenation-active catalyst component comprising one or more metals of transition group 8 of the Periodic Table and b.) one or more solid, acidic cocatalysts, wherein the hydrogenating amination is carried out in the presence of aqueous ammonia or aqueous amine of the formula (III) and at least one organic solvent miscible with ammonia or the aqueous amine of the formula (III). |
