发明名称 ANTIBODIES WITH SIMULTANEOUS SUBSITE SPECIFICITIES TO PROTEIN AND LIPID EPITOPES
摘要 <p num="1"><br/><br/><br/>Antibodies and method of making antibodies, either monoclonal or polyclonal <br/>wherein said antibodies have dual or multi-specific binding capacity to more <br/>than one type of antigenic epitope. The antibodies have simultaneous or <br/>independent recognition subsites to each of the epitopes. Antigenic epitopes <br/>include lipids, peptides, proteins, amino acid sequences, sugars and <br/>carbohydrates. Monoclonal antibodies and a method of making monoclonal <br/>antibodies of the invention include monoclonal antibodies that are broadly <br/>neutralizing to HIV-I or other envelop viruses wherein the monoclonal antibody <br/>has subsites that simultaneously recognize protein and lipid epitopes from the <br/>virus.<br/></p>
申请公布号 CA2623517(A1) 申请公布日期 2007.04.05
申请号 CA20062623517 申请日期 2006.09.22
申请人 ALVING, CARL R.;WALTER REED ARMY INSTITUTE OF RESEARCH (WRAIR) 发明人 ALVING, CARL R.
分类号 C07K16/46;A61K39/21;C07K16/10;C07K16/18 主分类号 C07K16/46
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