发明名称 PROCESS FOR THE STEREOSELECTIVE PREPARATION OF (-)-HALOFENATE AND INTERMEDIATES THEREOF
摘要 <p num="1"><br/><br/><br/>The present invention provides a compounds the formula (IV): and methods for <br/>producing an .alpha.-(phenoxy)phenylacetic acid compound of the formula: <br/>wherein R1 is a member selected from the group consisting of: each R2 is a <br/>member independently selected from the group consisting of (C1- C4)alkyl, <br/>halo, (C1-C4)haloalkyl, amino, (C1-C4 aminoalkyl, amido, (C1- C4)amidoalkyl, <br/>(C1-C4)sulfonylalkyl, (C1-C4)sulfamylalkyl, (C1-C4)allcoxy, (C1- <br/>C4)heteroalkyl, carboxy and nitro; the subscript n is 1 when R1 has the <br/>formula (a) or (b) and 2 when R1 has the formula (c) or (d); the subscript m <br/>is an integer of from O to 3; * indicates a carbon which is enriched in one <br/>stereoisomeric configuration; and the wavy line indicates the point of <br/>attachment of R1; and compounds .<br/>
申请公布号 CA2623350(A1) 申请公布日期 2007.04.05
申请号 CA20062623350 申请日期 2006.09.21
申请人 METABOLEX, INC. 发明人 CHEN, XIN;MA, JINGYUAN;ZHAO, ZUCHUN;CHENG, PENG;ZHU, YAN
分类号 A61K31/4025;A61K31/40;A61K31/495;A61K31/5375;C07D207/06;C07D241/04;C07D265/30 主分类号 A61K31/4025
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