发明名称 METHODS AND COMPOSITIONS FOR MANAGING PSYCHOTIC DISORDERS
摘要 Compositions for treating psychotic disorders comprise a first ingredient and a second ingredient, wherein the first ingredient comprises at least one antipsychotic agent selected from the group consisting of ziprasidone, olanzapine and risperidone and the second ingredient comprises at least one anticonvulsant selected from the group consisting of zonisamide and topiramate. Methods of treating psychotic disorders, symptoms associated with psychotic disorders, and side effects associated with antipsychotic agents, comprise administering a first ingredient and a second ingredient, wherein the first ingredient comprises at least one antipsychotic agent selected from the group consisting of ziprasidone, olanzapine and risperidone and the second ingredient comprises at least one anticonvulsant selected from the group consisting of zonisamide and topiramate. The second ingredient of the compositions and methods may further comprise an antidepressant. In various embodiments, the antipsychotic agent and the anticonvulsant act synergistically to alleviate symptoms and/or side effects associated with psychotic disorders and their treatment.
申请公布号 WO2006130522(A3) 申请公布日期 2007.04.05
申请号 WO2006US20616 申请日期 2006.05.25
申请人 OREXIGEN THERAPEUTICS, INC.;TOLLEFSON, GARY 发明人 TOLLEFSON, GARY
分类号 A61K31/496;A61K31/423;A61K31/519;A61K31/551;A61K31/7048;A61P25/18 主分类号 A61K31/496
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