摘要 |
PROBLEM TO BE SOLVED: To provide a means for inhibiting the activity of a TGF-βII type receptor, and treating keloid, hypertrophic scar and scar. SOLUTION: This skin lotion is obtained by incorporating a compound expressed by general formula (1) [wherein, R<SB>1</SB>to R<SB>10</SB>are each independently H, a 1-4C alkyloxy or hydroxy] or its salt in skin lotion. As the compound expressed by the general formula (1), morin is preferable. The content of the compound expressed by the general formula (1) and/or its salt is preferably 0.1-10 mass%, the skin lotion is preferably used for a treatment of the keloid, hypertrophic scar or scar, and the subjects of treatment are preferably the keloid, hypertrophic scar and scar caused by the TGF-β. COPYRIGHT: (C)2007,JPO&INPIT
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