COATED MICROSPHERES

摘要

The invention relates to microspheres, more particularly to microspheres comprising a core, a functional layer and a solid oxide coating, wherein the functional layer forms an intermediate layer between the core and the solid oxide coating. The invention also relates to methods of making such microspheres. The microspheres may further comprise a priming layer, wherein the priming layer forms an intermediate layer between the solid oxide coating and the functional layer. The microspheres may further comprise an anchoring agent, wherein the functional layer is anchored to the core by binding to the anchoring agent. The functional layer comprises a magnetizable agent, a fluorescent agent, a coloured agent or a radioactive agent. Coupling agents such as silane and a germane are used.