发明名称 CYCLOALKYL AMINO-HYDANTOIN COMPOUNDS AND USE THEREOF FOR ß-SECRETASE MODULATION
摘要 The present invention provides a 2-amino-5-cycloalkyl-hydantoin compound of formula (I) The present invention also provides methods and compositions for the inhibition of ß-secretase (BACE) and the treatment of ß-amyloid deposits and neurofibrillary tangles.
申请公布号 WO2007016012(A3) 申请公布日期 2007.04.05
申请号 WO2006US28580 申请日期 2006.07.24
申请人 WYETH;MALAMAS, MICHAEL SOTIRIOS;GUNAWAN, IWAN SUWANDI;ERDEI, JAMES JOSEPH;NOWAK, PAWEL;STOCK, JOSEPH, RAYMOND;YAN, YINFA 发明人 MALAMAS, MICHAEL SOTIRIOS;GUNAWAN, IWAN SUWANDI;ERDEI, JAMES JOSEPH;NOWAK, PAWEL;STOCK, JOSEPH, RAYMOND;YAN, YINFA
分类号 C07D233/88;A61K31/4168;A61P25/28;C07D233/54;C07D405/06;C07D405/10;C07D405/12;C07D409/06 主分类号 C07D233/88
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