CYCLOALKYL AMINO-HYDANTOIN COMPOUNDS AND USE THEREOF FOR ß-SECRETASE MODULATION
摘要
The present invention provides a 2-amino-5-cycloalkyl-hydantoin compound of formula (I) The present invention also provides methods and compositions for the inhibition of ß-secretase (BACE) and the treatment of ß-amyloid deposits and neurofibrillary tangles.
申请公布号
WO2007016012(A3)
申请公布日期
2007.04.05
申请号
WO2006US28580
申请日期
2006.07.24
申请人
WYETH;MALAMAS, MICHAEL SOTIRIOS;GUNAWAN, IWAN SUWANDI;ERDEI, JAMES JOSEPH;NOWAK, PAWEL;STOCK, JOSEPH, RAYMOND;YAN, YINFA
发明人
MALAMAS, MICHAEL SOTIRIOS;GUNAWAN, IWAN SUWANDI;ERDEI, JAMES JOSEPH;NOWAK, PAWEL;STOCK, JOSEPH, RAYMOND;YAN, YINFA