| 摘要 |
<p>Gamma-carboline of formula (I), the N-oxide form, the pharmaceutically acceptable addition salt and the stereochemically isomeric form thereof, wherein R1 is hydrogen, aryl or C1-6 alkyl substituted with aryl, R2 is each independently a halogen, hydroxy, C1-6 alkyl, C1-6 alkyloxy or nitro, n is 0, 1, 2 or 3; Alk is C1-6 alkanediyl, D is optionally substituted saturated or unsaturated nitrogen containing heterocycle, and aryl is optionally substituted phenyl, process for their preparation and composition containing its. Gamma-carbolines of formula (I) have a great therapeutic breadth.</p> |
