| 摘要 |
The invention concerns a compound of the formula (I); wherein Ring A is heterocyclyl; m is 0-4 and each R<SUP>1 </SUP>is a group such as hydroxy, halo, trifluoromethyl and cyano; Ring B is ring such as thienyl, thiadiazolyl, thiazolyl, pyrimidyl, pyrazinyl, pyridazinyl and pyridyl; R<SUP>2 </SUP>is halo and n is 0-2; and each R<SUP>4 </SUP>is a group such as hydroxy, halo, trifluoromethyl and cyano; p is 0-4; and R<SUP>3 </SUP>is amino or hydroxy; or pharmaceutically-acceptable salts or in-vivo-hydrolysable ester or amide thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by histone deacetylase. |
