COMPOSITIONS AND METHODS OF USING CHONDROITINASE ABCI MUTANTS
摘要
One aspect of the present invention relates to mutants of chondroitinase ABCI. Such chondroitinase ABCI mutants exhibit altered chondroitin lyase activity or increased resistance to inactivation from stressors including exposure to UV light or heat. Methods of using chondroitinase ABCI mutant enzymes are also provided.
申请公布号
CA2623635(A1)
申请公布日期
2007.04.05
申请号
CA20062623635
申请日期
2006.09.26
申请人
ACORDA THERAPEUTICS, INC.
发明人
CAGGIANO, ANTHONY O.;IACI, JENNIFER;VECCHIONE, ANDREA;MARKENSOHN, ELIZABETH