METHOD TO PROFILE AND TREAT ABNORMAL CELLS

摘要

Advantage is taken of identifying the differences in glutathione-S-transfera se (GST) complements of unwanted tissues and cells as compared to normal tissues and cells to evaluate therapeutic protocols designed to treat conditions characterized by, for example, tumor cells or infectious agents. Therapeutic modulators which affe ct preferentially the GST complement of normal or unwanted cells or tissues can thereby also be selected for use in combinatio n with drugs which serve as substrates for GST.