发明名称 |
Imidazole derivatives as Raf kinase inhibitors |
摘要 |
Novel compounds (I) and their use as pharmaceuticals particularly as Raf kinase inhibitors for the treatment of neurotraumatic diseases, cancer, chronic neurodegeneration, pain, migraine and cardiac hypertrophy wherein Ar is a group of formula a) or b).
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申请公布号 |
US7199137(B2) |
申请公布日期 |
2007.04.03 |
申请号 |
US20030380891 |
申请日期 |
2003.03.20 |
申请人 |
SMITHKLINE BEECHAM PLC |
发明人 |
DEAN DAVID KENNETH;TAKLE ANDREW KENNETH;WILSON DAVID MATTHEW |
分类号 |
A61K31/4439;A61K31/444;A61K31/4545;A61K31/496;A61K31/497;A61K31/5377;A61K49/00;A61P9/00;A61P9/10;A61P25/00;A61P25/04;A61P25/06;A61P25/28;A61P29/00;A61P35/00;A61P43/00;C07D401/04;C07D401/14;C07D405/14 |
主分类号 |
A61K31/4439 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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